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The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
Kobayashi, Motoi; Usui-Kawanishi, Fumitake; Karasawa, Tadayoshi; Kimura, Hiroaki; Watanabe, Sachiko; Mise, Nathan; Kayama, Fujio; Kasahara, Tadashi; Hasebe, Naoyuki; Takahashi, Masafumi.
Afiliación
  • Kobayashi M; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
  • Usui-Kawanishi F; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
  • Karasawa T; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
  • Kimura H; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
  • Watanabe S; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
  • Mise N; Department of Environmental and Preventive Medicine, Jichi Medical University, Tochigi, Japan.
  • Kayama F; Department of Environmental and Preventive Medicine, Jichi Medical University, Tochigi, Japan.
  • Kasahara T; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
  • Hasebe N; Department of Medicine, Division of Cardiovascular, Respiratory and Neurology, Asahikawa Medical University, Hokkaido, Japan.
  • Takahashi M; Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.
PLoS One ; 12(5): e0176676, 2017.
Article en En | MEDLINE | ID: mdl-28493895
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ouabaína / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Inflamación / Miocardio Límite: Animals Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Japón
Texto completo
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XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Ouabaína / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR / Inflamación / Miocardio Límite: Animals Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Japón