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Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models.
Irukayama-Tomobe, Yoko; Ogawa, Yasuhiro; Tominaga, Hiromu; Ishikawa, Yukiko; Hosokawa, Naoto; Ambai, Shinobu; Kawabe, Yuki; Uchida, Shuntaro; Nakajima, Ryo; Saitoh, Tsuyoshi; Kanda, Takeshi; Vogt, Kaspar; Sakurai, Takeshi; Nagase, Hiroshi; Yanagisawa, Masashi.
Afiliación
  • Irukayama-Tomobe Y; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Ogawa Y; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Tominaga H; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Ishikawa Y; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Hosokawa N; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Ambai S; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Kawabe Y; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Uchida S; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Nakajima R; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Saitoh T; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Kanda T; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Vogt K; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Sakurai T; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Nagase H; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.
  • Yanagisawa M; International Institute for Integrative Sleep Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan yanagisawa.masa.fu@u.tsukuba.ac.jp.
Proc Natl Acad Sci U S A ; 114(22): 5731-5736, 2017 05 30.
Article en En | MEDLINE | ID: mdl-28507129
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vigilia / Benzamidas / Cataplejía / Trastornos del Sueño del Ritmo Circadiano / Receptores de Orexina / Promotores de la Vigilia / Orexinas / Compuestos de Anilina / Narcolepsia Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article País de afiliación: Japón
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Vigilia / Benzamidas / Cataplejía / Trastornos del Sueño del Ritmo Circadiano / Receptores de Orexina / Promotores de la Vigilia / Orexinas / Compuestos de Anilina / Narcolepsia Tipo de estudio: Diagnostic_studies Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2017 Tipo del documento: Article País de afiliación: Japón