Coronary microvascular dysfunction in diabetes mellitus.
J Int Med Res
; 45(6): 1901-1929, 2017 Dec.
Article
en En
| MEDLINE
| ID: mdl-28643578
ABSTRACT
The significance, mechanisms and consequences of coronary microvascular dysfunction associated with diabetes mellitus are topics into which we have insufficient insight at this time. It is widely recognized that endothelial dysfunction that is caused by diabetes in various vascular beds contributes to a wide range of complications and exerts unfavorable effects on microcirculatory regulation. The coronary microcirculation is precisely regulated through a number of interconnected physiological processes with the purpose of matching local blood flow to myocardial metabolic demands. Dysregulation of this network might contribute to varying degrees of pathological consequences. This review discusses the most important findings regarding coronary microvascular dysfunction in diabetes from pre-clinical and clinical perspectives.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Vasos Coronarios
/
Diabetes Mellitus
/
Microvasos
Límite:
Humans
Idioma:
En
Revista:
J Int Med Res
Año:
2017
Tipo del documento:
Article
País de afiliación:
Croacia