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Modular approach for bimodal antibacterial surfaces combining photo-switchable activity and sustained biocidal release.
Pallavicini, Piersandro; Bassi, Barbara; Chirico, Giuseppe; Collini, Maddalena; Dacarro, Giacomo; Fratini, Emiliano; Grisoli, Pietro; Patrini, Maddalena; Sironi, Laura; Taglietti, Angelo; Moritz, Marcel; Sorzabal-Bellido, Ioritz; Susarrey-Arce, Arturo; Latter, Edward; Beckett, Alison J; Prior, Ian A; Raval, Rasmita; Diaz Fernandez, Yuri A.
Afiliación
  • Pallavicini P; Department of Chemistry and Centre for Health Technology, University of Pavia, Pavia, Italy. piersandro.pallavicini@unipv.it.
  • Bassi B; Department of Chemistry and Centre for Health Technology, University of Pavia, Pavia, Italy.
  • Chirico G; Department of Physics, University Milano-Bicocca, Milano, Italy.
  • Collini M; Department of Physics, University Milano-Bicocca, Milano, Italy.
  • Dacarro G; Department of Chemistry and Centre for Health Technology, University of Pavia, Pavia, Italy.
  • Fratini E; Department of Chemistry "Ugo Schiff" and CSGI, University of Florence, Florence, Italy.
  • Grisoli P; Department of Pharmaceutical Sciences, University of Pavia, Pavia, Italy.
  • Patrini M; Department of Physics, University of Pavia, Pavia, Italy.
  • Sironi L; Department of Physics, University Milano-Bicocca, Milano, Italy.
  • Taglietti A; Department of Chemistry and Centre for Health Technology, University of Pavia, Pavia, Italy. angelo.taglietti@unipv.it.
  • Moritz M; Open Innovation Hub for Antimicrobial Surfaces, University of Liverpool, Liverpool, UK.
  • Sorzabal-Bellido I; Open Innovation Hub for Antimicrobial Surfaces, University of Liverpool, Liverpool, UK.
  • Susarrey-Arce A; Open Innovation Hub for Antimicrobial Surfaces, University of Liverpool, Liverpool, UK.
  • Latter E; Open Innovation Hub for Antimicrobial Surfaces, University of Liverpool, Liverpool, UK.
  • Beckett AJ; Biomedical EM Unit, School of Biomedical Sciences, University of Liverpool, Liverpool, UK.
  • Prior IA; Biomedical EM Unit, School of Biomedical Sciences, University of Liverpool, Liverpool, UK.
  • Raval R; Open Innovation Hub for Antimicrobial Surfaces, University of Liverpool, Liverpool, UK. raval@liverpool.ac.uk.
  • Diaz Fernandez YA; Open Innovation Hub for Antimicrobial Surfaces, University of Liverpool, Liverpool, UK. yuridiaz@liverpool.ac.uk.
Sci Rep ; 7(1): 5259, 2017 07 12.
Article en En | MEDLINE | ID: mdl-28701753
ABSTRACT
Photo-responsive antibacterial surfaces combining both on-demand photo-switchable activity and sustained biocidal release were prepared using sequential chemical grafting of nano-objects with different geometries and functions. The multi-layered coating developed incorporates a monolayer of near-infrared active silica-coated gold nanostars (GNS) decorated by silver nanoparticles (AgNP). This modular approach also enables us to unravel static and photo-activated contributions to the overall antibacterial performance of the surfaces, demonstrating a remarkable synergy between these two mechanisms. Complementary microbiological and imaging evaluations on both planktonic and surface-attached bacteria provided new insights on these distinct but cooperative effects.
Asunto(s)

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Materiales Biocompatibles Revestidos / Nanopartículas del Metal / Rayos Láser / Antibacterianos Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Italia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Bacterias / Materiales Biocompatibles Revestidos / Nanopartículas del Metal / Rayos Láser / Antibacterianos Idioma: En Revista: Sci Rep Año: 2017 Tipo del documento: Article País de afiliación: Italia
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