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The therapeutic effects of Longikaurin A, a natural ent-kauranoid, in esophageal squamous cell carcinoma depend on ROS accumulation and JNK/p38 MAPK activation.
Che, Yun; Wang, Jingnan; Yuan, Zuyang; Li, Yuan; Lu, Zhiliang; Zhang, Zhirong; Zhang, Jinyao; Wan, Jun; Sun, Handong; Chen, Zhaoli; Pu, Jianxin; He, Jie.
Afiliación
  • Che Y; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: cheyun47@yeah.net.
  • Wang J; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: wind.1060@163.com.
  • Yuan Z; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: doc_yuanzuyang@yeah.net.
  • Li Y; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: liyuanpumc@gmail.com.
  • Lu Z; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: zhiliangpumc@gmail.com.
  • Zhang Z; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: zhangjess@126.com.
  • Zhang J; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: jinyao6690@126.com.
  • Wan J; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China. Electronic address: junwan1@yeah.net.
  • Sun H; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China. Electronic address: handongsun@yeah.net.
  • Chen Z; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: chenzhaoli@126.com.
  • Pu J; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China. Electronic address: pujianxin@mail.kib.ac.cn.
  • He J; Department of Thoracic Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China. Electronic address: prof.jiehe@gmail.com.
Toxicol Lett ; 280: 106-115, 2017 10 05.
Article en En | MEDLINE | ID: mdl-28801140
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Especies Reactivas de Oxígeno / Diterpenos de Tipo Kaurano / Proteínas Quinasas JNK Activadas por Mitógenos / Proteínas Quinasas p38 Activadas por Mitógenos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Toxicol Lett Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Carcinoma de Células Escamosas / Especies Reactivas de Oxígeno / Diterpenos de Tipo Kaurano / Proteínas Quinasas JNK Activadas por Mitógenos / Proteínas Quinasas p38 Activadas por Mitógenos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Toxicol Lett Año: 2017 Tipo del documento: Article