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The Autoimmune Risk Variant PTPN22 C1858T Alters B Cell Tolerance at Discrete Checkpoints and Differentially Shapes the Naive Repertoire.
Metzler, Genita; Dai, Xuezhi; Thouvenel, Christopher D; Khim, Socheath; Habib, Tania; Buckner, Jane H; Rawlings, David J.
Afiliación
  • Metzler G; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101.
  • Dai X; Department of Immunology, University of Washington School of Medicine, Seattle, WA 98195.
  • Thouvenel CD; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101.
  • Khim S; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101.
  • Habib T; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, WA 98101.
  • Buckner JH; Translational Research Program, Benaroya Research Institute, Seattle, WA 98101; and.
  • Rawlings DJ; Translational Research Program, Benaroya Research Institute, Seattle, WA 98101; and.
J Immunol ; 199(7): 2249-2260, 2017 10 01.
Article en En | MEDLINE | ID: mdl-28801357
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Variación Genética / Linfocitos B / Proteína Tirosina Fosfatasa no Receptora Tipo 22 / Tolerancia Inmunológica Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Immunol Año: 2017 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Variación Genética / Linfocitos B / Proteína Tirosina Fosfatasa no Receptora Tipo 22 / Tolerancia Inmunológica Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans Idioma: En Revista: J Immunol Año: 2017 Tipo del documento: Article