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Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase.
Santa Maria, John P; Park, Yumi; Yang, Lihu; Murgolo, Nicholas; Altman, Michael D; Zuck, Paul; Adam, Greg; Chamberlin, Chad; Saradjian, Peter; Dandliker, Peter; Boshoff, Helena I M; Barry, Clifton E; Garlisi, Charles; Olsen, David B; Young, Katherine; Glick, Meir; Nickbarg, Elliott; Kutchukian, Peter S.
Afiliación
  • Santa Maria JP; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States.
  • Park Y; National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, United States.
  • Yang L; Department of Chemistry, Merck Sharp & Dohme Corp. , Kenilworth, New Jersey, United States.
  • Murgolo N; Department of Information & Analytics, Merck Sharp & Dohme Corp. , Kenilworth, New Jersey, United States.
  • Altman MD; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States.
  • Zuck P; Research Science, Merck Sharp & Dohme Corp. , North Wales, Pennsylvania, United States.
  • Adam G; Department of Pharmacology, Merck Sharp & Dohme Corp. , North Wales, Pennsylvania, United States.
  • Chamberlin C; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States.
  • Saradjian P; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States.
  • Dandliker P; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States.
  • Boshoff HIM; National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, United States.
  • Barry CE; National Institute of Allergy and Infectious Diseases , Bethesda, Maryland, United States.
  • Garlisi C; Department of Pharmacology, Merck Sharp & Dohme Corp. , Kenilworth, New Jersey, United States.
  • Olsen DB; Neglected Tropical Disease Discovery, Merck Sharp & Dohme Corp. , West Point, Pennsylvania, United States.
  • Young K; Neglected Tropical Disease Discovery, Merck Sharp & Dohme Corp. , West Point, Pennsylvania, United States.
  • Glick M; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States.
  • Nickbarg E; Department of Pharmacology, Merck Sharp & Dohme Corp. , Boston, Massachusetts, United States.
  • Kutchukian PS; Modeling & Informatics, Merck Research Laboratories , Boston, Massachusetts, United States.
ACS Chem Biol ; 12(9): 2448-2456, 2017 09 15.
Article en En | MEDLINE | ID: mdl-28806050
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 3_ND Problema de salud: 2_enfermedades_transmissibles / 3_neglected_diseases / 3_tuberculosis Asunto principal: Tetrahidrofolato Deshidrogenasa / Antagonistas del Ácido Fólico / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: ACS Chem Biol Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 3_ND Problema de salud: 2_enfermedades_transmissibles / 3_neglected_diseases / 3_tuberculosis Asunto principal: Tetrahidrofolato Deshidrogenasa / Antagonistas del Ácido Fólico / Mycobacterium tuberculosis / Antituberculosos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: ACS Chem Biol Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos