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B-cell receptor sequencing of anti-citrullinated protein antibody (ACPA) IgG-expressing B cells indicates a selective advantage for the introduction of N-glycosylation sites during somatic hypermutation.
Vergroesen, Rochelle D; Slot, Linda M; Hafkenscheid, Lise; Koning, Marvyn T; van der Voort, Ellen I H; Grooff, Christine A; Zervakis, George; Veelken, Hendrik; Huizinga, Tom W J; Rispens, Theo; Scherer, Hans U; Toes, René E M.
Afiliación
  • Vergroesen RD; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Slot LM; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Hafkenscheid L; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Koning MT; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • van der Voort EIH; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Grooff CA; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Zervakis G; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • Veelken H; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands.
  • Huizinga TWJ; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Rispens T; Department of Immunopathology, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, Amsterdam, The Netherlands.
  • Scherer HU; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
  • Toes REM; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.
Ann Rheum Dis ; 77(6): 956-958, 2018 06.
Article en En | MEDLINE | ID: mdl-28835463
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Artritis Reumatoide / Autoanticuerpos / Receptores de Antígenos de Linfocitos B / Hipermutación Somática de Inmunoglobulina Límite: Humans Idioma: En Revista: Ann Rheum Dis Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos Cíclicos / Artritis Reumatoide / Autoanticuerpos / Receptores de Antígenos de Linfocitos B / Hipermutación Somática de Inmunoglobulina Límite: Humans Idioma: En Revista: Ann Rheum Dis Año: 2018 Tipo del documento: Article País de afiliación: Países Bajos