[Chronic venous diseases: valvular function and leukocyte-endothelial interaction, possibilities of pharmacotherapy]. / Khronicheskie zabolevaniia ven: funktsiia klapanov i leikotsitarno-éndotelial'noe vzaimodeistvie, vozmozhnosti farmakoterapii.
Angiol Sosud Khir
; 23(3): 89-96, 2017.
Article
en Ru
| MEDLINE
| ID: mdl-28902819
ABSTRACT
This article provides a review of the literature focusing on the data elucidating the pathogenesis of chronic venous diseases from the positions of macrohaemodynamic (venous valvular function) and microcirculatory impairments. Presented herein are confirmations of the interaction between two important mechanisms, as well as the literature data concerning the role of the venous microvalvular structures and possible haemodynamic impairments in functional venous insufficiency. Also presented are substantiations in confirmation of the theory of leukocyte-endothelial interaction, forming the basis for contemporary understanding of the pathogenesis of chronic venous diseases. This is followed by elucidating the role of venoactive drugs in conservative treatment of patients with chronic venous diseases, and, finally, touching upon current problems and promising approaches to solve them.
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Insuficiencia Venosa
/
Endotelio Vascular
/
Células Epiteliales
/
Válvulas Venosas
/
Leucocitos
Límite:
Humans
Idioma:
Ru
Revista:
Angiol Sosud Khir
Asunto de la revista:
CARDIOLOGIA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Rusia