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Inhibition of the deubiquitinase USP5 leads to c-Maf protein degradation and myeloma cell apoptosis.
Wang, Siyu; Juan, Jiaxiang; Zhang, Zubin; Du, Yanyun; Xu, Yujia; Tong, Jiefei; Cao, Biyin; Moran, Michael F; Zeng, Yuanying; Mao, Xinliang.
Afiliación
  • Wang S; Jiangsu Key Laboratory for Translational Research and Therapeutics of Neuro-Psycho- Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
  • Juan J; Jiangsu Key Laboratory for Translational Research and Therapeutics of Neuro-Psycho- Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
  • Zhang Z; Jiangsu Key Laboratory for Translational Research and Therapeutics of Neuro-Psycho- Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
  • Du Y; Jiangsu Key Laboratory for Translational Research and Therapeutics of Neuro-Psycho- Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
  • Xu Y; Jiangsu Key Laboratory for Translational Research and Therapeutics of Neuro-Psycho- Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
  • Tong J; Program in Molecular Structure and Function, The Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto M5G 0A4, Canada.
  • Cao B; Jiangsu Key Laboratory for Translational Research and Therapeutics of Neuro-Psycho- Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
  • Moran MF; Program in Molecular Structure and Function, The Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto M5G 0A4, Canada.
  • Zeng Y; Department of Oncology, Suzhou Municipal Hospital East Campus, Suzhou 215100, China.
  • Mao X; Jiangsu Key Laboratory for Translational Research and Therapeutics of Neuro-Psycho- Diseases, Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, Jiangsu 215123, China.
Cell Death Dis ; 8(9): e3058, 2017 09 21.
Article en En | MEDLINE | ID: mdl-28933784
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_cardiovascular_diseases / 6_lymphomas_multiple_myeloma Asunto principal: Endopeptidasas / Apoptosis / Proteínas Proto-Oncogénicas c-maf / Proteolisis / Mieloma Múltiple Límite: Humans Idioma: En Revista: Cell Death Dis Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_cardiovascular_diseases / 6_lymphomas_multiple_myeloma Asunto principal: Endopeptidasas / Apoptosis / Proteínas Proto-Oncogénicas c-maf / Proteolisis / Mieloma Múltiple Límite: Humans Idioma: En Revista: Cell Death Dis Año: 2017 Tipo del documento: Article País de afiliación: China