Resequencing Epithelial Sodium Channel Genes Identifies Rare Variants Associated With Blood Pressure Salt-Sensitivity: The GenSalt Study.

Gu, Xiaoying; Gu, Dongfeng; He, Jiang; Rao, Dabeeru C; Hixson, James E; Chen, Jichun; Li, Jianxin; Huang, Jianfeng; Wu, Xigui; Rice, Treva K; Shimmin, Lawrence C; Kelly, Tanika N

Gu, Xiaoying; Gu, Dongfeng; He, Jiang; Rao, Dabeeru C; Hixson, James E; Chen, Jichun; Li, Jianxin; Huang, Jianfeng; Wu, Xigui; Rice, Treva K; Shimmin, Lawrence C; Kelly, Tanika N.

Afiliación

Gu X; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Gu D; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine and School of Medicine, New Orleans, Louisiana, USA.
He J; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Rao DC; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine and School of Medicine, New Orleans, Louisiana, USA.
Hixson JE; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA.
Chen J; Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston, Texas, USA.
Li J; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Huang J; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wu X; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Rice TK; Department of Epidemiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Shimmin LC; Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA.
Kelly TN; Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Houston, Texas, USA.

Am J Hypertens ; 31(2): 205-211, 2018 01 12.

Article en En | MEDLINE | ID: mdl-29036630

Asunto(s)

Presión Sanguínea/genética; Canales Epiteliales de Sodio/genética; Hipertensión; Cloruro de Sodio Dietético/metabolismo; Adulto; Determinación de la Presión Sanguínea; Femenino; Predisposición Genética a la Enfermedad; Humanos; Hipertensión/metabolismo; Hipertensión/fisiopatología; Masculino; Polimorfismo de Nucleótido Simple

Palabras clave

blood pressure; capillary-based sequencing; dietary sodium; epithelial 1 alpha subunit (SCNN1A); genetics; hypertension; mean arterial pressure; rare variants; salt sensitivity; single nucleotide polymorphism; sodium channel epithelial 1 beta subunit (SCNN1B); sodium channel epithelial 1 gamma subunit (SCNN1G)

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Presión Sanguínea / Cloruro de Sodio Dietético / Canales Epiteliales de Sodio / Hipertensión Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male Idioma: En Revista: Am J Hypertens Asunto de la revista: ANGIOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: China

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