Linkage studies in a large fragile X family.
Am J Hum Genet
; 43(5): 684-8, 1988 Nov.
Article
en En
| MEDLINE
| ID: mdl-2903666
ABSTRACT
We have analyzed the segregation of five loci in the region Xq27/28 in a large family affected by the fragile X syndrome. The marker DXS115 (767) is shown to be polymorphic with the enzyme PstI, as well as with BstXI. This marker will be useful in the analysis of both fragile X and haemophilia A families. The data presented here are consistent with the following order of loci Xcen-F9-DXS105(cX55.7,55E)-DXS98(4D-8)- FRAXA-DXS52(St14)-DXS115(767)-qter.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Aberraciones Cromosómicas Sexuales
/
Síndrome del Cromosoma X Frágil
/
Ligamiento Genético
Límite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
Am J Hum Genet
Año:
1988
Tipo del documento:
Article
País de afiliación:
Reino Unido