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Efficient Encapsulation of Fluorinated Drugs in the Confined Space of Water-Dispersible Fluorous Supraparticles.
Pigliacelli, Claudia; Maiolo, Daniele; Haataja, Johannes S; Amenitsch, Heinz; Michelet, Claire; Sánchez Moreno, Paola; Tirotta, Ilaria; Metrangolo, Pierangelo; Baldelli Bombelli, Francesca.
Afiliación
  • Pigliacelli C; Laboratory of Supramolecular and BioNano Materials (SupraBioNanoLab), Department of Chemistry, Materials, and Chemical Engineering "Giulio Natta", Politecnico di Milano, Via L. Mancinelli 7, 20131, Milan, Italy.
  • Maiolo D; Department of Applied Physics, Aalto University School of Science, P.O. Box 11000, 00076, Aalto, Finland.
  • Nonappa; Laboratory of Supramolecular and BioNano Materials (SupraBioNanoLab), Department of Chemistry, Materials, and Chemical Engineering "Giulio Natta", Politecnico di Milano, Via L. Mancinelli 7, 20131, Milan, Italy.
  • Haataja JS; Department of Applied Physics, Aalto University School of Science, P.O. Box 11000, 00076, Aalto, Finland.
  • Amenitsch H; Department of Bioproducts and Biosystems, Aalto University School of Chemical Engineering, P.O. Box 16100, 00076, Aalto, Finland.
  • Michelet C; Department of Applied Physics, Aalto University School of Science, P.O. Box 11000, 00076, Aalto, Finland.
  • Sánchez Moreno P; Elettra-Sincrotrone Trieste S.C.p.A., Strada Statale 14-km 163,5, 34149 Basovizza, Trieste, Italia.
  • Tirotta I; Laboratory of Supramolecular and BioNano Materials (SupraBioNanoLab), Department of Chemistry, Materials, and Chemical Engineering "Giulio Natta", Politecnico di Milano, Via L. Mancinelli 7, 20131, Milan, Italy.
  • Metrangolo P; Laboratory of Supramolecular and BioNano Materials (SupraBioNanoLab), Department of Chemistry, Materials, and Chemical Engineering "Giulio Natta", Politecnico di Milano, Via L. Mancinelli 7, 20131, Milan, Italy.
  • Baldelli Bombelli F; Laboratory of Supramolecular and BioNano Materials (SupraBioNanoLab), Department of Chemistry, Materials, and Chemical Engineering "Giulio Natta", Politecnico di Milano, Via L. Mancinelli 7, 20131, Milan, Italy.
Angew Chem Int Ed Engl ; 56(51): 16186-16190, 2017 12 18.
Article en En | MEDLINE | ID: mdl-29105938
ABSTRACT
Fluorophobic-driven assemblies of gold nanomaterials were stabilized into water-dispersible fluorous supraparticles by the film-forming protein hydrophobin II. The strategy makes use of fluorous nanomaterials of different dimensions to engineer size and inner functionalization of the resulting confined space. The inner fluorous compartments allow efficient encapsulation and transport of high loadings of partially fluorinated drug molecules in water.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzoxazinas / Celecoxib / Flúor / Leflunamida Idioma: En Revista: Angew Chem Int Ed Engl Año: 2017 Tipo del documento: Article País de afiliación: Italia
Texto completo
Añadir a Mi BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Benzoxazinas / Celecoxib / Flúor / Leflunamida Idioma: En Revista: Angew Chem Int Ed Engl Año: 2017 Tipo del documento: Article País de afiliación: Italia