Exercise improves recognition memory and synaptic plasticity in the prefrontal cortex for rats modelling vascular dementia.

Dong, Juntao; Zhao, Jingpu; Lin, Yangyang; Liang, Huiying; He, Xiaokuo; Zheng, Xiuyuan; Sui, Minghong; Zhuang, Zhiqiang; Yan, Tiebin

Dong, Juntao; Zhao, Jingpu; Lin, Yangyang; Liang, Huiying; He, Xiaokuo; Zheng, Xiuyuan; Sui, Minghong; Zhuang, Zhiqiang; Yan, Tiebin.

Afiliación

Dong J; a Department of Rehabilitation Medicine , Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou , China.
Zhao J; a Department of Rehabilitation Medicine , Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou , China.
Lin Y; b Department of Rehabilitation Medicine , The Sixth Affiliated Hospital, Sun Yat-sen University , Guangzhou , China.
Liang H; c Department of Rehabilitation Medicine , People's Hospital of Zhongshan City , Zhongshan , China.
He X; d Department of Rehabilitation Medicine , Taihe Hospital , Shiyan , China.
Zheng X; a Department of Rehabilitation Medicine , Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou , China.
Sui M; e Department of Rehabilitation Medicine , Nanshan Hospital , Shenzhen , China.
Zhuang Z; a Department of Rehabilitation Medicine , Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou , China.
Yan T; a Department of Rehabilitation Medicine , Sun Yat-sen Memorial Hospital, Sun Yat-sen University , Guangzhou , China.

Neurol Res ; 40(1): 68-77, 2018 Jan.

Article en En | MEDLINE | ID: mdl-29126372

Asunto(s)

Demencia Vascular; Trastornos de la Memoria/etiología; Trastornos de la Memoria/rehabilitación; Plasticidad Neuronal/fisiología; Condicionamiento Físico Animal/métodos; Corteza Prefrontal/patología; Reconocimiento en Psicología/fisiología; Animales; Demencia Vascular/complicaciones; Demencia Vascular/patología; Demencia Vascular/rehabilitación; Modelos Animales de Enfermedad; Conducta Exploratoria; Regulación de la Expresión Génica/fisiología; Masculino; Proteínas de la Membrana/metabolismo; Proteínas del Tejido Nervioso/metabolismo; Ratas; Ratas Wistar

Palabras clave

AMPA: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; BDNF: brain-derived neurotrophic factor; BSA: bovine serum albumin; CREB: AMP-response element binding protein; CaMKII: calcium/calmodulin dependent protein kinase II; EGF: epidermal growth factor; FES: functional electrical stimulation; FGF: fibroblast growth factor; GluR1: alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor 1; LTP: long-term potentiation; MAP-2: microtubule-associated protein 2; NMDA: N-methyl-D-aspartic acid; NOLT: novel object location test; NORT: novel object recognition test; NR1: N-methyl-D-aspartic acid receptor 1; PFC: prefrontal cortex; PSD-95: postsynaptic density 95; SYN: synapsin I; SYP: synaptophysin; VD: vascular dementia; Vascular dementia; exercise; functional electrical stimulation; recognition memory; synaptic plasticity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Condicionamiento Físico Animal / Demencia Vascular / Corteza Prefrontal / Reconocimiento en Psicología / Trastornos de la Memoria / Plasticidad Neuronal Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Neurol Res Año: 2018 Tipo del documento: Article País de afiliación: China

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