Geissoschizine synthase controls flux in the formation of monoterpenoid indole alkaloids in a Catharanthus roseus mutant.

Qu, Yang; Thamm, Antje M K; Czerwinski, Matthew; Masada, Sayaka; Kim, Kyung Hee; Jones, Graham; Liang, Ping; De Luca, Vincenzo

Qu, Yang; Thamm, Antje M K; Czerwinski, Matthew; Masada, Sayaka; Kim, Kyung Hee; Jones, Graham; Liang, Ping; De Luca, Vincenzo.

Afiliación

Qu Y; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada.
Thamm AMK; Havas Life Bird and Schulte, Urachstrasse 19, 79102, Freiburg, Germany.
Czerwinski M; Grain Farmers of Ontario, 679 Southgate Drive, Guelph, ON, N1G 4S2, Canada.
Masada S; Division of Pharmacognosy, Phytochemistry and Narcotics, National Institute of Health Sciences, Ministry of Health, Labor and Welfare, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo, 158-8501, Japan.
Kim KH; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada.
Jones G; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada.
Liang P; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada.
De Luca V; Department of Biological Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, ON, L2S 3A1, Canada. vdeluca@brocku.ca.

Planta ; 247(3): 625-634, 2018 Mar.

Article en En | MEDLINE | ID: mdl-29147812

Asunto(s)

Carbolinas/metabolismo; Catharanthus/metabolismo; Proteínas de Plantas/metabolismo; Alcaloides de Triptamina Secologanina/metabolismo; Catharanthus/enzimología; Catharanthus/genética; Glucosidasas/metabolismo; Complejos Multienzimáticos/metabolismo; Mutación/genética; Vinblastina/análogos & derivados; Vinblastina/metabolismo; beta-Glucosidasa/metabolismo

Palabras clave

Geissoschizine synthase; Heteroyohimbine synthase; Mutant screen; Strictosidine ß-glucosidase; Tetrahydroalstonine synthase; Virus-induced gene silencing

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas de Plantas / Carbolinas / Catharanthus / Alcaloides de Triptamina Secologanina Idioma: En Revista: Planta Año: 2018 Tipo del documento: Article País de afiliación: Canadá

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