The VEGF paradox: Does diabetic retinopathy protect from age related macular degeneration?
Med Hypotheses
; 109: 156-161, 2017 Nov.
Article
en En
| MEDLINE
| ID: mdl-29150277
ABSTRACT
Age-related macular disease (AMD) and diabetic retinopathy (DR) are prevalent diseases. Vascular endothelial growth factor (VEGF) related retinal neovascularization is a common feature in both. Consequently, both pathologies are treated with anti-VEGF therapy. We have previously reported a lower incidence of AMD in patients with DR compared to controls. The present study hypothesizes that DR in stages in which the concentration of intravitreal VEGF is increased, might have a protective role for both the onset and development of AMD.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oxígeno
/
Neovascularización Retiniana
/
Neovascularización Coroidal
/
Factor A de Crecimiento Endotelial Vascular
/
Retinopatía Diabética
/
Degeneración Macular
Tipo de estudio:
Prognostic_studies
Límite:
Aged
/
Humans
/
Middle aged
Idioma:
En
Revista:
Med Hypotheses
Año:
2017
Tipo del documento:
Article
País de afiliación:
Argentina