Oral submucous fibrosis: an etiological dilemma.
J Exp Ther Oncol
; 12(2): 163-166, 2017 Nov.
Article
en En
| MEDLINE
| ID: mdl-29161786
ABSTRACT
OBJECTIVE:
Oral Submucous Fibrosis (OSF), is a well-recognized, oral potentially malignant disorder predominantly affecting the South- Asian countries. OSF causes unique generalized fibrosis of the submucosal oral soft tissues, resulting in marked rigidity of the oral mucosa leading to progressive inability to open the mouth, rigidity of lips and difficulty in protruding the tongue. In this review we have discussed the multifactorial etiology of this potentially malignant disorder, including Chillies, Nutritional Deficiencies, Inducible nitric oxide synthsis (iNOS), genetic and immunological predisposition; and most importantly the role of areca nut and the effect of copper content in it.Palabras clave
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Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Fibrosis de la Submucosa Bucal
Tipo de estudio:
Etiology_studies
Límite:
Humans
Idioma:
En
Revista:
J Exp Ther Oncol
Asunto de la revista:
NEOPLASIAS
/
TERAPIA POR MEDICAMENTOS
Año:
2017
Tipo del documento:
Article
País de afiliación:
India