Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1&#945;.

Chandra, Goutam; Kundu, Madhuchhanda; Rangasamy, Suresh B; Dasarathy, Sridevi; Ghosh, Supurna; Watson, Richard; Pahan, Kalipada

Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1α.

Chandra, Goutam; Kundu, Madhuchhanda; Rangasamy, Suresh B; Dasarathy, Sridevi; Ghosh, Supurna; Watson, Richard; Pahan, Kalipada.

Afiliación

Chandra G; Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison St, Suite Cohn 310, Chicago, IL, 60612, USA.
Kundu M; Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison St, Suite Cohn 310, Chicago, IL, 60612, USA.
Rangasamy SB; Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison St, Suite Cohn 310, Chicago, IL, 60612, USA.
Dasarathy S; Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison St, Suite Cohn 310, Chicago, IL, 60612, USA.
Ghosh S; Revalesio Corporation, 1200 East D Street, Tacoma, WA, 98421, USA.
Watson R; Revalesio Corporation, 1200 East D Street, Tacoma, WA, 98421, USA.
Pahan K; Department of Neurological Sciences, Rush University Medical Center, 1735 West Harrison St, Suite Cohn 310, Chicago, IL, 60612, USA. Kalipada_Pahan@rush.edu.

J Neuroimmune Pharmacol ; 13(2): 143-162, 2018 06.

Article en En | MEDLINE | ID: mdl-29188424

Asunto(s)

Mitocondrias/efectos de los fármacos; Neuronas/efectos de los fármacos; Biogénesis de Organelos; Soluciones Farmacéuticas/farmacología; Animales; Línea Celular; Ratones; Mitocondrias/metabolismo; Neuronas/metabolismo; Coactivador 1-alfa del Receptor Activado por Proliferadores de Peroxisomas gamma/metabolismo; Fosfatidilinositol 3-Quinasas/metabolismo; Cloruro de Sodio/farmacología; Regulación hacia Arriba

Palabras clave

Mitochondrial biogenesis; Modified saline; Nanobubbles; Neurons; PGC1α; PI3 kinase

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Biogénesis de Organelos / Soluciones Farmacéuticas / Mitocondrias / Neuronas Límite: Animals Idioma: En Revista: J Neuroimmune Pharmacol Asunto de la revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA / NEUROLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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