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Systems Pharmacology Dissection of Cholesterol Regulation Reveals Determinants of Large Pharmacodynamic Variability between Cell Lines.
Blattmann, Peter; Henriques, David; Zimmermann, Michael; Frommelt, Fabian; Sauer, Uwe; Saez-Rodriguez, Julio; Aebersold, Ruedi.
Afiliación
  • Blattmann P; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zurich, Switzerland. Electronic address: blattmann@imsb.biol.ethz.ch.
  • Henriques D; IIM-CSIC Spanish Council for Scientific Research, (Bio)Process Engineering Group, C/Eduardo Cabello 6, 36208 Vigo, Spain.
  • Zimmermann M; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zurich, Switzerland.
  • Frommelt F; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zurich, Switzerland.
  • Sauer U; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zurich, Switzerland.
  • Saez-Rodriguez J; RWTH-Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), MTZ Pauwelstrasse 19, D-52074 Aachen, Germany; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
  • Aebersold R; Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Auguste-Piccard-Hof 1, 8093 Zurich, Switzerland; Faculty of Science, University of Zurich, Zurich, Switzerland. Electronic address: aebersold@imsb.biol.ethz.ch.
Cell Syst ; 5(6): 604-619.e7, 2017 12 27.
Article en En | MEDLINE | ID: mdl-29226804
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Farmacología / Análisis de Sistemas / Resistencia a Medicamentos / Colesterol / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Syst Año: 2017 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Farmacología / Análisis de Sistemas / Resistencia a Medicamentos / Colesterol / Modelos Biológicos Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cell Syst Año: 2017 Tipo del documento: Article