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Novel conjugates of tacrine with 1,2,4,-thiadiazole as highly effective cholinesterase inhibitors, blockers of NMDA receptors, and antioxidants.
Makhaeva, G F; Grigoriev, V V; Proshin, A N; Kovaleva, N V; Rudakova, E V; Boltneva, N P; Serkov, I V; Bachurin, S O.
Afiliación
  • Makhaeva GF; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia. gmakh@ipac.ac.ru.
  • Grigoriev VV; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
  • Proshin AN; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
  • Kovaleva NV; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
  • Rudakova EV; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
  • Boltneva NP; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
  • Serkov IV; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
  • Bachurin SO; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka, Moscow Region, Russia.
Dokl Biochem Biophys ; 477(1): 405-409, 2017 Nov.
Article en En | MEDLINE | ID: mdl-29297118
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tacrina / Tiadiazoles / Inhibidores de la Colinesterasa / Receptores de N-Metil-D-Aspartato / Antioxidantes Límite: Humans Idioma: En Revista: Dokl Biochem Biophys Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Rusia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Tacrina / Tiadiazoles / Inhibidores de la Colinesterasa / Receptores de N-Metil-D-Aspartato / Antioxidantes Límite: Humans Idioma: En Revista: Dokl Biochem Biophys Asunto de la revista: BIOFISICA / BIOQUIMICA Año: 2017 Tipo del documento: Article País de afiliación: Rusia