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Part II: New candidates of pyrazole-benzimidazole conjugates as checkpoint kinase 2 (Chk2) inhibitors.
Galal, Shadia A; Khairat, Sarah H M; Ali, Hamed I; Shouman, Samia A; Attia, Yasmin M; Ali, Mamdouh M; Mahmoud, Abeer E; Abdel-Halim, Abeer H; Fyiad, Amal A; Tabll, Ashraf; El-Shenawy, Reem; El Abd, Yasmine S; Ramdan, Raghda; El Diwani, Hoda I.
Afiliación
  • Galal SA; Department of Chemistry of Natural and Microbial Products, Division of Pharmaceutical and Drug Industries, National Research Centre, Cairo, 12622, Egypt. Electronic address: sh12galal@hotmail.com.
  • Khairat SHM; Department of Chemistry of Natural and Microbial Products, Division of Pharmaceutical and Drug Industries, National Research Centre, Cairo, 12622, Egypt.
  • Ali HI; Department of Pharmaceutical Sciences, Texas A&M University Irma Lerma Rangel College of Pharmacy Kingsville, TX 78363, United States; Department of Pharmaceutical Chemistry, College of Pharmacy, Helwan University, Cairo, Egypt.
  • Shouman SA; Department of Cancer Biology, National Cancer Institute, Cairo University, Egypt.
  • Attia YM; Department of Cancer Biology, National Cancer Institute, Cairo University, Egypt.
  • Ali MM; Department of Biochemistry, Division of Genetic Engineering and Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • Mahmoud AE; Department of Biochemistry, Division of Genetic Engineering and Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • Abdel-Halim AH; Department of Biochemistry, Division of Genetic Engineering and Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • Fyiad AA; Department of Biochemistry, Division of Genetic Engineering and Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • Tabll A; Department of Microbial Biotechnology, Division of Genetic Engineering & Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • El-Shenawy R; Department of Microbial Biotechnology, Division of Genetic Engineering & Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • El Abd YS; Department of Microbial Biotechnology, Division of Genetic Engineering & Biotechnology, National Research Centre, 12622, Cairo, Egypt.
  • Ramdan R; Radiobiology Unit, Belgian Nuclear Research Center (SCK•CEN), Mol, Belgium; Department of Basic Medical Sciences, Physiology Group, Ghent University, Ghent, Belgium.
  • El Diwani HI; Department of Chemistry of Natural and Microbial Products, Division of Pharmaceutical and Drug Industries, National Research Centre, Cairo, 12622, Egypt.
Eur J Med Chem ; 144: 859-873, 2018 Jan 20.
Article en En | MEDLINE | ID: mdl-29316526
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Bencimidazoles / Inhibidores de Proteínas Quinasas / Quinasa de Punto de Control 2 / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Pirazoles / Bencimidazoles / Inhibidores de Proteínas Quinasas / Quinasa de Punto de Control 2 / Antineoplásicos Límite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Año: 2018 Tipo del documento: Article