Alkyl polyglucoside vs. ethoxylated surfactant-based microemulsions as vehicles for two poorly water-soluble drugs: physicochemical characterization and in vivo skin performance.

Pajic, Natasa Z Bubic; Todosijevic, Marija N; Vuleta, Gordana M; Cekic, Nebojsa D; Dobricic, Vladimir D; Vucen, Sonja R; Calija, Bojan R; Lukic, Milica Z; Ilic, Tanja M; Savic, Snezana D

Pajic, Natasa Z Bubic; Todosijevic, Marija N; Vuleta, Gordana M; Cekic, Nebojsa D; Dobricic, Vladimir D; Vucen, Sonja R; Calija, Bojan R; Lukic, Milica Z; Ilic, Tanja M; Savic, Snezana D.

Afiliación

Pajic NZB; 1Department of Pharmaceutical Technology and Cosmetology Faculty of Medicine, University of Banja Luka, 78000 Banja Luka Bosnia and Herzegovina.
Todosijevic MN; 2Department of Pharmaceutical Technology and Cosmetology Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.
Vuleta GM; 2Department of Pharmaceutical Technology and Cosmetology Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.
Cekic ND; 3Faculty of Technology, University of Nis, 16000 Leskovac, Serbia.
Dobricic VD; 5Department of Pharmaceutical Chemistry, Faculty of Pharmacy University of Belgrade, Belgrade, Serbia.
Vucen SR; 6School of Pharmacy, University College Cork, Cork, Ireland.
Calija BR; 2Department of Pharmaceutical Technology and Cosmetology Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.
Lukic MZ; 2Department of Pharmaceutical Technology and Cosmetology Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.
Ilic TM; 2Department of Pharmaceutical Technology and Cosmetology Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.
Savic SD; 2Department of Pharmaceutical Technology and Cosmetology Faculty of Pharmacy, University of Belgrade, 11221 Belgrade, Serbia.

Acta Pharm ; 67(4): 415-439, 2017 Dec 20.

Article en En | MEDLINE | ID: mdl-29337676

Asunto(s)

Caprilatos/farmacocinética; Emulsiones/farmacología; Glucósidos/farmacología; Vehículos Farmacéuticos/farmacocinética; Polisorbatos/farmacología; Piel/metabolismo; Tensoactivos/farmacología; Adapaleno/farmacología; Administración Cutánea; Adulto; Caprilatos/química; Emulsiones/química; Glucósidos/química; Humanos; Imidazoles/farmacología; Microscopía de Polarización; Vehículos Farmacéuticos/química; Polisorbatos/química; Piel/efectos de los fármacos; Pruebas de Irritación de la Piel; Solubilidad; Espectroscopía Infrarroja por Transformada de Fourier; Tensoactivos/química; Tiofenos/farmacología

Palabras clave

adapalene; alkyl polyglucoside; biocompatible microemulsion; ethoxylated surfactant; in vivo skin irritation; sertaconazole nitrate

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 1_ASSA2030 Problema de salud: 1_medicamentos_vacinas_tecnologias Asunto principal: Polisorbatos / Piel / Tensoactivos / Vehículos Farmacéuticos / Caprilatos / Emulsiones / Glucósidos Límite: Adult / Humans Idioma: En Revista: Acta Pharm Asunto de la revista: FARMACIA / FARMACOLOGIA Año: 2017 Tipo del documento: Article

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