Thymoma-associated myasthenia gravis and LGI1-encephalitis, with nephrotic syndrome post-thymectomy.
J Neuroimmunol
; 317: 100-102, 2018 04 15.
Article
en En
| MEDLINE
| ID: mdl-29395322
ABSTRACT
Thymoma is associated with a wide spectrum of autoimmune paraneoplastic syndromes, though it is uncommon for multiple paraneoplastic syndromes to be present in a single individual. We report a rare case of an elderly gentleman who was found to have thymoma-associated myasthenia gravis and LGI1-encephalitis with myokymia, who presented with nephrotic syndrome (minimal change glomerulopathy) after thymectomy. The latter two paraneoplastic syndromes had manifested when prednisolone was tapered down to low dose. This case serves to remind neurologists that apart from paraneoplastic neurological manifestations, thymoma may also be associated with renal disease. Nephropathy in myasthenia patients with thymoma should be properly evaluated, as it is treatable with immunotherapy, and it may even occur post-thymectomy.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Síndromes Paraneoplásicos
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Timoma
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Neoplasias del Timo
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Encefalitis
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Miastenia Gravis
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Síndrome Nefrótico
Tipo de estudio:
Risk_factors_studies
Límite:
Aged
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Humans
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Male
Idioma:
En
Revista:
J Neuroimmunol
Año:
2018
Tipo del documento:
Article