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Pharmacological activation of autophagy favors the clearing of intracellular aggregates of misfolded prion protein peptide to prevent neuronal death.
Thellung, Stefano; Scoti, Beatrice; Corsaro, Alessandro; Villa, Valentina; Nizzari, Mario; Gagliani, Maria Cristina; Porcile, Carola; Russo, Claudio; Pagano, Aldo; Tacchetti, Carlo; Cortese, Katia; Florio, Tullio.
Afiliación
  • Thellung S; Section of Pharmacology, Department of Internal Medicine (DiMI), and Centre of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy.
  • Scoti B; Section of Pharmacology, Department of Internal Medicine (DiMI), and Centre of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy.
  • Corsaro A; Section of Pharmacology, Department of Internal Medicine (DiMI), and Centre of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy.
  • Villa V; Section of Pharmacology, Department of Internal Medicine (DiMI), and Centre of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy.
  • Nizzari M; Section of Pharmacology, Department of Internal Medicine (DiMI), and Centre of Excellence for Biomedical Research (CEBR), University of Genova, Genova, Italy.
  • Gagliani MC; Section of Human Anatomy, Department of Experimental Medicine (DIMES), School of Medicine, University of Genova, Genova, Italy.
  • Porcile C; Department of Health Sciences, University of Molise, Campobasso, Italy.
  • Russo C; Department of Health Sciences, University of Molise, Campobasso, Italy.
  • Pagano A; Section of Human Anatomy, Department of Experimental Medicine (DIMES), School of Medicine, University of Genova, Genova, Italy.
  • Tacchetti C; Ospedale Policlinico San Martino, IRCCS per l'Oncologia, Genova, Italy.
  • Cortese K; Centro Imaging Sperimentale, IRCCS Istituto Scientifico San Raffaele, Milano, Italy.
  • Florio T; Vita-Salute San Raffaele University, Milano, Italy.
Cell Death Dis ; 9(2): 166, 2018 02 07.
Article en En | MEDLINE | ID: mdl-29416016
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Autofagia / Pliegue de Proteína / Espacio Intracelular / Agregado de Proteínas / Proteínas Priónicas / Neuronas Límite: Animals Idioma: En Revista: Cell Death Dis Año: 2018 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Péptidos / Autofagia / Pliegue de Proteína / Espacio Intracelular / Agregado de Proteínas / Proteínas Priónicas / Neuronas Límite: Animals Idioma: En Revista: Cell Death Dis Año: 2018 Tipo del documento: Article País de afiliación: Italia