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Structure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infection.
Kalas, Vasilios; Hibbing, Michael E; Maddirala, Amarendar Reddy; Chugani, Ryan; Pinkner, Jerome S; Mydock-McGrane, Laurel K; Conover, Matt S; Janetka, James W; Hultgren, Scott J.
Afiliación
  • Kalas V; Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110.
  • Hibbing ME; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Maddirala AR; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.
  • Chugani R; Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110.
  • Pinkner JS; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
  • Mydock-McGrane LK; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.
  • Conover MS; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO 63110.
  • Janetka JW; Center for Women's Infectious Disease Research, Washington University School of Medicine, St. Louis, MO 63110.
  • Hultgren SJ; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
Proc Natl Acad Sci U S A ; 115(12): E2819-E2828, 2018 03 20.
Article en En | MEDLINE | ID: mdl-29507247
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 3_ND Problema de salud: 2_enfermedades_transmissibles / 3_neglected_diseases / 3_zoonosis Asunto principal: Infecciones Urinarias / Adhesión Bacteriana / Adhesinas de Escherichia coli / Antibacterianos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 3_ND Problema de salud: 2_enfermedades_transmissibles / 3_neglected_diseases / 3_zoonosis Asunto principal: Infecciones Urinarias / Adhesión Bacteriana / Adhesinas de Escherichia coli / Antibacterianos Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article