Metabolism of the synthetic cannabinoids AMB-CHMICA and 5C-AKB48 in pooled human hepatocytes and rat hepatocytes analyzed by UHPLC-(IMS)-HR-MS<sup>E</sup>.

Mardal, Marie; Dalsgaard, Petur Weihe; Qi, Bing; Mollerup, Christian Brinch; Annaert, Pieter; Linnet, Kristian

Metabolism of the synthetic cannabinoids AMB-CHMICA and 5C-AKB48 in pooled human hepatocytes and rat hepatocytes analyzed by UHPLC-(IMS)-HR-MS^E.

Mardal, Marie; Dalsgaard, Petur Weihe; Qi, Bing; Mollerup, Christian Brinch; Annaert, Pieter; Linnet, Kristian.

Afiliación

Mardal M; Section of Forensic Chemistry, University of Copenhagen, Department of Forensic Medicines, Frederik V's vej 11, 2100 København Ø, Denmark. Electronic address: marie.mardal@sund.ku.dk.
Dalsgaard PW; Section of Forensic Chemistry, University of Copenhagen, Department of Forensic Medicines, Frederik V's vej 11, 2100 København Ø, Denmark.
Qi B; Drug delivery and Disposition, KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, O&N2, Herestraat 49, 3000 Leuven, Belgium.
Mollerup CB; Section of Forensic Chemistry, University of Copenhagen, Department of Forensic Medicines, Frederik V's vej 11, 2100 København Ø, Denmark.
Annaert P; Drug delivery and Disposition, KU Leuven, Department of Pharmaceutical and Pharmacological Sciences, O&N2, Herestraat 49, 3000 Leuven, Belgium.
Linnet K; Section of Forensic Chemistry, University of Copenhagen, Department of Forensic Medicines, Frederik V's vej 11, 2100 København Ø, Denmark.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1083: 189-197, 2018 Apr 15.

Article en En | MEDLINE | ID: mdl-29549742

Asunto(s)

Cannabinoides/metabolismo; Cromatografía Líquida de Alta Presión/métodos; Hepatocitos/metabolismo; Drogas Ilícitas/metabolismo; Adamantano/análisis; Adamantano/química; Adamantano/metabolismo; Animales; Cannabinoides/análisis; Cannabinoides/química; Humanos; Drogas Ilícitas/análisis; Drogas Ilícitas/química; Indoles/análisis; Indoles/química; Indoles/metabolismo; Espectrometría de Masas/métodos; Ratas

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cannabinoides / Drogas Ilícitas / Cromatografía Líquida de Alta Presión / Hepatocitos Límite: Animals / Humans Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Asunto de la revista: ENGENHARIA BIOMEDICA Año: 2018 Tipo del documento: Article

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