In vitro activity of tedizolid and comparator agents against clinical Gram-positive isolates recovered from patients with cancer.
Diagn Microbiol Infect Dis
; 91(4): 351-353, 2018 Aug.
Article
en En
| MEDLINE
| ID: mdl-29661529
ABSTRACT
A total of 248 Gram-positive isolates from cancer patients were tested for in-vitro susceptibility to tedizolid and 3 comparator agents using CLSI broth microdilution methodology. Tedizolid inhibited 97% of isolates at ≤0.5µg/ml. It was active against all Gram-positive species and consistently had 8 fold lower MICs than linezolid, although based on % susceptibility using CLSI breakpoints, most isolates were also susceptible to the comparators. Tedizolid was active against MRSA isolates with vancomycin MICs of ≥1.0µg/ml.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Tetrazoles
/
Infecciones por Bacterias Grampositivas
/
Oxazolidinonas
/
Farmacorresistencia Bacteriana
/
Bacterias Grampositivas
/
Antibacterianos
Límite:
Humans
Idioma:
En
Revista:
Diagn Microbiol Infect Dis
Año:
2018
Tipo del documento:
Article