GoldiRunx and Remembering Cytotoxic Memory.

Mikami, Yohei; Kanno, Yuka

Mikami, Yohei; Kanno, Yuka.

Afiliación

Mikami Y; Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Kanno Y; Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address: kannoy@mail.nih.gov.

Immunity ; 48(4): 614-615, 2018 04 17.

Article en En | MEDLINE | ID: mdl-29669241

RESUMEN

The molecular basis for T cell memory differentiation remains elusive. Wang et al. (2018) identify Runx3 as an initiating transcription factor that specifies regulatory regions required for cytotoxic T cell (CTL) memory differentiation early after TCR signaling and constrains the ability of T-bet to drive terminal effector generation.

Asunto(s)

Cromatina; Linfocitos T Citotóxicos; Diferenciación Celular; Regulación de la Expresión Génica; Memoria; Factores de Transcripción

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Cromatina / Linfocitos T Citotóxicos Tipo de estudio: Prognostic_studies Idioma: En Revista: Immunity Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos

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