Supramolecular nanofiber of pyrene-lactose conjugates and its two-photon fluorescence imaging.
Bioorg Chem
; 79: 126-130, 2018 09.
Article
en En
| MEDLINE
| ID: mdl-29747128
ABSTRACT
A lactose modified pyrene derivative (Py-Lac) was synthesized, with which novel twisted supramolecular nanofibers in diameter about 20â¯nm were constructed by self-assembly. The nanofibers showed solid-state fluorescence between 400â¯nm and 650â¯nm with the maximum emission at 495â¯nm. Furthermore, its recognition reaction with PNA lectin was investigated by fluorescence spectra and turbidity assays. It is interesting found that the supramolecular assembly as multivalent glycocluster exhibited unique and selectively binding interactions with PNA lectin with the binding constant of 5.74â¯×â¯106â¯M-1. Moreover, compound Py-Lac showed two-photon fluorescence imaging with Hep G2 cells.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Pirenos
/
Sustancias Macromoleculares
/
Nanofibras
/
Colorantes Fluorescentes
/
Lactosa
Límite:
Humans
Idioma:
En
Revista:
Bioorg Chem
Año:
2018
Tipo del documento:
Article
País de afiliación:
China