Facile fabrication of microfluidic surface-enhanced Raman scattering devices via lift-up lithography.

Wu, Yuanzi; Jiang, Ye; Zheng, Xiaoshan; Jia, Shasha; Zhu, Zhi; Ren, Bin; Ma, Hongwei

Facile fabrication of microfluidic surface-enhanced Raman scattering devices via lift-up lithography.

Wu, Yuanzi; Jiang, Ye; Zheng, Xiaoshan; Jia, Shasha; Zhu, Zhi; Ren, Bin; Ma, Hongwei.

Afiliación

Wu Y; College of Biological Science and Engineering, Fuzhou University, Fuzhou 350002, People's Republic of China.
Jiang Y; College of Biological Science and Engineering, Fuzhou University, Fuzhou 350002, People's Republic of China.
Zheng X; State Key Laboratory of Physical Chemistry of Solid Surfaces, the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, and Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen 361005, People's Republ
Jia S; State Key Laboratory of Physical Chemistry of Solid Surfaces, the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, and Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen 361005, People's Republ
Zhu Z; State Key Laboratory of Physical Chemistry of Solid Surfaces, the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, and Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen 361005, People's Republ
Ren B; State Key Laboratory of Physical Chemistry of Solid Surfaces, the MOE Key Laboratory of Spectrochemical Analysis and Instrumentation, College of Chemistry and Chemical Engineering, and Collaborative Innovation Center of Chemistry of Energy Materials, Xiamen University, Xiamen 361005, People's Republ
Ma H; Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou 215125, People's Republic of China.

R Soc Open Sci ; 5(4): 172034, 2018 Apr.

Article en En | MEDLINE | ID: mdl-29765657

RESUMEN

We describe a facile and low-cost approach for a flexibly integrated surface-enhanced Raman scattering (SERS) substrate in microfluidic chips. Briefly, a SERS substrate was fabricated by the electrostatic assembling of gold nanoparticles, and shaped into designed patterns by subsequent lift-up soft lithography. The SERS micro-pattern could be further integrated within microfluidic channels conveniently. The resulting microfluidic SERS chip allowed ultrasensitive in situ SERS monitoring from the transparent glass window. With its advantages in simplicity, functionality and cost-effectiveness, this method could be readily expanded into optical microfluidic fabrication for biochemical applications.

Palabras clave

lift-up lithography; microfluidics; surface-enhanced Raman scattering substrate

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: R Soc Open Sci Año: 2018 Tipo del documento: Article