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Fluorescence and Cytotoxicity of Cadmium Sulfide Quantum Dots Stabilized on Clay Nanotubes.
Stavitskaya, Anna V; Novikov, Andrei A; Kotelev, Mikhail S; Kopitsyn, Dmitry S; Rozhina, Elvira V; Ishmukhametov, Ilnur R; Fakhrullin, Rawil F; Ivanov, Evgenii V; Lvov, Yuri M; Vinokurov, Vladimir A.
Afiliación
  • Stavitskaya AV; Functional Aluminosilicate Nanomaterials Lab, Gubkin University, Moscow 119991, Russia. stavitsko@mail.ru.
  • Novikov AA; Functional Aluminosilicate Nanomaterials Lab, Gubkin University, Moscow 119991, Russia. novikov.a@gubkin.ru.
  • Kotelev MS; Functional Aluminosilicate Nanomaterials Lab, Gubkin University, Moscow 119991, Russia. kain@inbox.ru.
  • Kopitsyn DS; Functional Aluminosilicate Nanomaterials Lab, Gubkin University, Moscow 119991, Russia. kopicin.d@inbox.ru.
  • Rozhina EV; Bionanotechnology Lab, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia. rozhinaelvira@gmail.com.
  • Ishmukhametov IR; Bionanotechnology Lab, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia. sal.ilnur@gmail.com.
  • Fakhrullin RF; Bionanotechnology Lab, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420008, Russia. kazanbio@gmail.com.
  • Ivanov EV; Functional Aluminosilicate Nanomaterials Lab, Gubkin University, Moscow 119991, Russia. ivanov166@list.ru.
  • Lvov YM; Functional Aluminosilicate Nanomaterials Lab, Gubkin University, Moscow 119991, Russia. ylvov@latech.edu.
  • Vinokurov VA; Institute for Micromanufacturing, Louisiana Tech University, Ruston, LA 71272, USA. ylvov@latech.edu.
Nanomaterials (Basel) ; 8(6)2018 May 31.
Article en En | MEDLINE | ID: mdl-29857546
Quantum dots (QD) are widely used for cellular labeling due to enhanced brightness, resistance to photobleaching, and multicolor light emissions. CdS and CdxZn1-xS nanoparticles with sizes of 6⁻8 nm were synthesized via a ligand assisted technique inside and outside of 50 nm diameter halloysite clay nanotubes (QD were immobilized on the tube's surface). The halloysite⁻QD composites were tested by labeling human skin fibroblasts and prostate cancer cells. In human cell cultures, halloysite⁻QD systems were internalized by living cells, and demonstrated intense and stable fluorescence combined with pronounced nanotube light scattering. The best signal stability was observed for QD that were synthesized externally on the amino-grafted halloysite. The best cell viability was observed for CdxZn1-xS QD immobilized onto the azine-grafted halloysite. The possibility to use QD clay nanotube core-shell nanoarchitectures for the intracellular labeling was demonstrated. A pronounced scattering and fluorescence by halloysite⁻QD systems allows for their promising usage as markers for biomedical applications.
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanomaterials (Basel) Año: 2018 Tipo del documento: Article País de afiliación: Rusia

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Idioma: En Revista: Nanomaterials (Basel) Año: 2018 Tipo del documento: Article País de afiliación: Rusia
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