Targeting Inflammatory T Helper Cells <i>via</i> Retinoic Acid-Related Orphan Receptor Gamma t Is Ineffective to Prevent Allo-Response-Driven Colitis.

Buchele, Vera; Abendroth, Benjamin; Büttner-Herold, Maike; Vogler, Tina; Rothamer, Johanna; Ghimire, Sakhila; Ullrich, Evelyn; Holler, Ernst; Neurath, Markus F; Hildner, Kai

Targeting Inflammatory T Helper Cells via Retinoic Acid-Related Orphan Receptor Gamma t Is Ineffective to Prevent Allo-Response-Driven Colitis.

Buchele, Vera; Abendroth, Benjamin; Büttner-Herold, Maike; Vogler, Tina; Rothamer, Johanna; Ghimire, Sakhila; Ullrich, Evelyn; Holler, Ernst; Neurath, Markus F; Hildner, Kai.

Afiliación

Buchele V; Department of Medicine 1, University Hospital Erlangen, University of Erlangen-Nuremberg, Kussmaul Campus for Medical Research, Erlangen, Germany.
Abendroth B; Department of Medicine 1, University Hospital Erlangen, University of Erlangen-Nuremberg, Kussmaul Campus for Medical Research, Erlangen, Germany.
Büttner-Herold M; Department of Nephropathology, Institute of Pathology, University Hospital Erlangen, Erlangen, Germany.
Vogler T; Department of Medicine 1, University Hospital Erlangen, University of Erlangen-Nuremberg, Kussmaul Campus for Medical Research, Erlangen, Germany.
Rothamer J; Department of Medicine 5, University Hospital Erlangen, University of Erlangen-Nuremberg, Erlangen, Germany.
Ghimire S; Department of Pediatric Stem Cell Transplantation and Immunology, Childrens Hospital, Johann Wolfgang Goethe University, Frankfurt, Germany.
Ullrich E; Department of Hematology and Oncology, Regensburg University Hospital, Regensburg, Germany.
Holler E; Department of Medicine 5, University Hospital Erlangen, University of Erlangen-Nuremberg, Erlangen, Germany.
Neurath MF; Department of Pediatric Stem Cell Transplantation and Immunology, Childrens Hospital, Johann Wolfgang Goethe University, Frankfurt, Germany.
Hildner K; Department of Hematology and Oncology, Regensburg University Hospital, Regensburg, Germany.

Front Immunol ; 9: 1138, 2018.

Article en En | MEDLINE | ID: mdl-29910804

Asunto(s)

Colitis/etiología; Colitis/metabolismo; Receptores de Ácido Retinoico/metabolismo; Linfocitos T Colaboradores-Inductores/inmunología; Linfocitos T Colaboradores-Inductores/metabolismo; Animales; Trasplante de Médula Ósea/efectos adversos; Trasplante de Médula Ósea/métodos; Células Cultivadas; Colitis/complicaciones; Colitis/terapia; Modelos Animales de Enfermedad; Femenino; Enfermedad Injerto contra Huésped; Ratones; Miembro 3 del Grupo F de la Subfamilia 1 de Receptores Nucleares/metabolismo; Receptores de Interleucina/genética; Receptores de Interleucina/metabolismo; Subgrupos de Linfocitos T/inmunología; Subgrupos de Linfocitos T/metabolismo; Trasplante Homólogo; Receptor de Ácido Retinoico gamma

Palabras clave

T helper 17 cells; basic leucine zipper transcription factor ATF-like; colitis; granulocyte-macrophage colony-stimulating factor; interleukin-23 receptor; intestinal graft-versus-host disease; retinoic acid-related orphan receptor gamma t

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Linfocitos T Colaboradores-Inductores / Receptores de Ácido Retinoico / Colitis Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Front Immunol Año: 2018 Tipo del documento: Article País de afiliación: Alemania

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