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Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau.P301S mouse model of Alzheimer's disease and frontotemporal dementia.
Ji, Mei; Xie, Xi-Xiu; Liu, Dong-Qun; Yu, Xiao-Lin; Zhang, Yue; Zhang, Ling-Xiao; Wang, Shao-Wei; Huang, Ya-Ru; Liu, Rui-Tian.
Afiliación
  • Ji M; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.
  • Xie XX; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Liu DQ; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.
  • Yu XL; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.
  • Zhang Y; University of Chinese Academy of Sciences, Beijing, 100049, China.
  • Zhang LX; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.
  • Wang SW; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.
  • Huang YR; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Shandong Agricultural University, Taian, 271018, China.
  • Liu RT; National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Haidian District, Beijing, 100190, China.
Alzheimers Res Ther ; 10(1): 55, 2018 06 19.
Article en En | MEDLINE | ID: mdl-29914543
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 4_TD Problema de salud: 2_enfermedades_transmissibles / 4_hepatitis Asunto principal: Proteínas tau / Trastornos del Conocimiento / Demencia Frontotemporal / Vacunas de Partículas Similares a Virus / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Animals Idioma: En Revista: Alzheimers Res Ther Año: 2018 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 / 4_TD Problema de salud: 2_enfermedades_transmissibles / 4_hepatitis Asunto principal: Proteínas tau / Trastornos del Conocimiento / Demencia Frontotemporal / Vacunas de Partículas Similares a Virus / Enfermedad de Alzheimer Tipo de estudio: Prognostic_studies Aspecto: Patient_preference Límite: Animals Idioma: En Revista: Alzheimers Res Ther Año: 2018 Tipo del documento: Article País de afiliación: China