Rapidly growing hepatocellular carcinoma recurrence during direct-acting antiviral treatment for chronic hepatitis C.
Clin J Gastroenterol
; 11(6): 497-500, 2018 Dec.
Article
en En
| MEDLINE
| ID: mdl-29948818
ABSTRACT
We herein report the case of a woman in her 80s with a recurrent hepatocellular carcinoma (HCC) tumor that rapidly increased in size during direct-acting antiviral (DAA) treatment. She suffered from HCC at her initial visit to our department and underwent hepatectomy. Thereafter, she underwent DAA treatment for chronic hepatitis C; however, her alpha-fetoprotein (AFP) level rapidly increased, and a liver tumor of > 1 cm in diameter was observed that had not been seen immediately before DAA treatment. She underwent hepatectomy again and moderate to poorly differentiated HCC was diagnosed. The patient's AFP level showed a rapid increase immediately after the start of DAA treatment; however, the increase ceased after the first month, and the influence from the surrounding environment of the tumor was considered to be temporary.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Antivirales
/
Carcinoma Hepatocelular
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Hepatitis C Crónica
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Neoplasias Hepáticas
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Recurrencia Local de Neoplasia
Límite:
Aged80
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Female
/
Humans
Idioma:
En
Revista:
Clin J Gastroenterol
Año:
2018
Tipo del documento:
Article
País de afiliación:
Japón