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Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial.
Yin, Ophelia Q P; Antman, Elliott M; Braunwald, Eugene; Mercuri, Michele F; Miller, Raymond; Morrow, David; Ruff, Christian T; Truitt, Kenneth; Weitz, Jeffrey I; Giugliano, Robert P.
Afiliación
  • Yin OQP; Daiichi-Sankyo Pharma Development, Basking Ridge, NJ (O.Q.P.Y., M.F.M., R.M., K.T.).
  • Antman EM; TIMI Study Group, Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (E.M.A., E.B., D.M., C.T.R., R.P.G.).
  • Braunwald E; TIMI Study Group, Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (E.M.A., E.B., D.M., C.T.R., R.P.G.).
  • Mercuri MF; Daiichi-Sankyo Pharma Development, Basking Ridge, NJ (O.Q.P.Y., M.F.M., R.M., K.T.).
  • Miller R; Daiichi-Sankyo Pharma Development, Basking Ridge, NJ (O.Q.P.Y., M.F.M., R.M., K.T.).
  • Morrow D; TIMI Study Group, Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (E.M.A., E.B., D.M., C.T.R., R.P.G.).
  • Ruff CT; TIMI Study Group, Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (E.M.A., E.B., D.M., C.T.R., R.P.G.).
  • Truitt K; Daiichi-Sankyo Pharma Development, Basking Ridge, NJ (O.Q.P.Y., M.F.M., R.M., K.T.).
  • Weitz JI; McMaster University and Thrombosis and Atherosclerosis Research Institute, Hamilton, Ontario, Canada (J.I.W.).
  • Giugliano RP; TIMI Study Group, Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (E.M.A., E.B., D.M., C.T.R., R.P.G.).
Circulation ; 138(18): 1963-1973, 2018 10 30.
Article en En | MEDLINE | ID: mdl-29967197
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Tiazoles / Factor Xa / Inhibidores del Factor Xa Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Circulation Año: 2018 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piridinas / Tiazoles / Factor Xa / Inhibidores del Factor Xa Tipo de estudio: Clinical_trials / Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Circulation Año: 2018 Tipo del documento: Article