Chiral supramolecular coordination cages as high-performance inhibitors against amyloid-ß aggregation.
Chem Commun (Camb)
; 54(63): 8725-8728, 2018 Aug 02.
Article
en En
| MEDLINE
| ID: mdl-30024578
ABSTRACT
Four pairs of chiral supramolecular coordination cages were facilely synthesized, and they could efficiently inhibit amyloid-ß (Aß) aggregation with a high inhibition rate of 0.64-0.86. This research provides a new perspective on the design of chiral Aß inhibitors using supramolecular metal-organic cages.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Péptidos beta-Amiloides
/
Sustancias Macromoleculares
/
Agregado de Proteínas
/
Estructuras Metalorgánicas
Límite:
Humans
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2018
Tipo del documento:
Article
País de afiliación:
China
