Toe dystonia in Parkinson's disease: Impact of subthalamic nucleus deep brain stimulation.
J Neurol Sci
; 392: 65-68, 2018 09 15.
Article
en En
| MEDLINE
| ID: mdl-30025235
ABSTRACT
BACKGROUND:
Off state toe dystonia (TD) is a symptom frequently encountered in Parkinson's disease (PD), but little is known about its evolution after subthalamic nucleus deep brain stimulation (STN-DBS).OBJECTIVE:
To analyze the prevalence and the evolution of TD in PD patients candidate to STN-DBS.METHODS:
Individual data of consecutive 130 PD patients who underwent STN-DBS between 2010 and 2015 were collected.RESULTS:
Data were successfully collected in 95 patients. TD affect 45.3% of the patients in our cohort. TD was present in 32.7% of patients before surgery and was alleviated by STN-DBS in 48% of the cases. Motor improvement provided by STN-DBS, levodopa-equivalent treatment diminution after surgery, disease duration or age at the time of surgery were not predictive of TD evolution. A younger age at PD diagnosis was significantly associated with TD resolution.CONCLUSION:
STN-DBS is partially efficient for TD but its evolution seems independent of significant predictive factors.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Enfermedad de Parkinson
/
Dedos del Pie
/
Núcleo Subtalámico
/
Estimulación Encefálica Profunda
/
Distonía
Tipo de estudio:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Neurol Sci
Año:
2018
Tipo del documento:
Article