The chemo- enzymatic synthesis of labeled l-amino acids and some of their derivatives.
J Radioanal Nucl Chem
; 317(2): 643-666, 2018.
Article
en En
| MEDLINE
| ID: mdl-30100649
ABSTRACT
This review compiles the combined chemical and enzymatic synthesis of aromatic l-amino acids (l-phenylalanine, l-tyrosine, l-DOPA, l-tryptophan, and their derivatives and precursors) specifically labeled with carbon and hydrogen isotopes, which were elaborated in our research group by the past 20 years. These compounds could be then employed to characterize the mechanisms of enzymatic reactions via kinetic and solvent isotope effects methods.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Idioma:
En
Revista:
J Radioanal Nucl Chem
Año:
2018
Tipo del documento:
Article
País de afiliación:
Polonia