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In vitro UGT1A1 inhibition by tyrosine kinase inhibitors and association with drug-induced hyperbilirubinemia.
Qosa, Hisham; Avaritt, Brittany R; Hartman, Neil R; Volpe, Donna A.
Afiliación
  • Qosa H; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD, 20993, USA.
  • Avaritt BR; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD, 20993, USA.
  • Hartman NR; Office of Generic Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD, 20993, USA.
  • Volpe DA; Office of Clinical Pharmacology, Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave., Silver Spring, MD, 20993, USA.
Cancer Chemother Pharmacol ; 82(5): 795-802, 2018 11.
Article en En | MEDLINE | ID: mdl-30105461
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Glucuronosiltransferasa / Inhibidores de Proteínas Quinasas / Hiperbilirrubinemia Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Chemother Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Microsomas Hepáticos / Glucuronosiltransferasa / Inhibidores de Proteínas Quinasas / Hiperbilirrubinemia Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Cancer Chemother Pharmacol Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos