IL-1ß-Mediated Up-Regulation of WT1D via miR-144-3p and Their Synergistic Effect with NF-&#954;B/COX-2/HIF-1&#945; Pathway on Cell Proliferation in LUAD.

Wu, Chen; Li, Xiaodong; Zhang, Dachuan; Xu, Bin; Hu, Wenwei; Zheng, Xiao; Zhu, Danxia; Zhou, Qi; Jiang, Jingting; Wu, Changping

IL-1ß-Mediated Up-Regulation of WT1D via miR-144-3p and Their Synergistic Effect with NF-κB/COX-2/HIF-1α Pathway on Cell Proliferation in LUAD.

Wu, Chen; Li, Xiaodong; Zhang, Dachuan; Xu, Bin; Hu, Wenwei; Zheng, Xiao; Zhu, Danxia; Zhou, Qi; Jiang, Jingting; Wu, Changping.

Afiliación

Wu C; Department of Oncology, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Li X; Institute of Cell Therapy, Soochow University, Changzhou, China.
Zhang D; Jiangsu Engineering Research Center for Tumor Immunotherapy, Changzhou, China.
Xu B; Department of Oncology, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Hu W; Jiangsu Engineering Research Center for Tumor Immunotherapy, Changzhou, China.
Zheng X; Department of Pathology, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Zhu D; Jiangsu Engineering Research Center for Tumor Immunotherapy, Changzhou, China.
Zhou Q; Department of Biological Treatment, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Jiang J; Department of Oncology, the Third Affiliated Hospital of Soochow University, Changzhou, China.
Wu C; Institute of Cell Therapy, Soochow University, Changzhou, China.

Cell Physiol Biochem ; 48(6): 2493-2502, 2018.

Article en En | MEDLINE | ID: mdl-30121641

Asunto(s)

Adenocarcinoma/patología; Interleucina-1beta/metabolismo; Neoplasias Pulmonares/patología; MicroARNs/metabolismo; Transducción de Señal; Proteínas WT1/metabolismo; Adenocarcinoma/tratamiento farmacológico; Adenocarcinoma/metabolismo; Adenocarcinoma del Pulmón; Anciano; Anciano de 80 o más Años; Animales; Antagomirs/metabolismo; Celecoxib/farmacología; Celecoxib/uso terapéutico; Línea Celular Tumoral; Ciclooxigenasa 2/genética; Ciclooxigenasa 2/metabolismo; Femenino; Humanos; Subunidad alfa del Factor 1 Inducible por Hipoxia/metabolismo; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/metabolismo; Masculino; Ratones; Ratones Desnudos; MicroARNs/antagonistas & inhibidores; MicroARNs/genética; Persona de Mediana Edad; FN-kappa B/genética; FN-kappa B/metabolismo; Interferencia de ARN; ARN Interferente Pequeño/metabolismo; Transducción de Señal/efectos de los fármacos; Proteínas WT1/antagonistas & inhibidores; Proteínas WT1/genética

Palabras clave

IL-1ß; LUAD; Proliferation; miR-144-3p

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Adenocarcinoma / Transducción de Señal / Proteínas WT1 / MicroARNs / Interleucina-1beta / Neoplasias Pulmonares Tipo de estudio: Prognostic_studies Límite: Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Cell Physiol Biochem Asunto de la revista: BIOQUIMICA / FARMACOLOGIA Año: 2018 Tipo del documento: Article País de afiliación: China

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