Topology- and linking number-controlled synthesis of a closed 3 link chain of single-stranded DNA.
Chem Commun (Camb)
; 54(72): 10156-10159, 2018 Sep 06.
Article
en En
| MEDLINE
| ID: mdl-30132764
ABSTRACT
In spite of remarkable progress in synthetic methodology, a closed three-link chain (one of the simplest but the most important topological isomers of [3]catenane) has never been prepared. Here we synthesized this isomer in high yield from three oligonucleotides which are designed to optimize various chemical and steric factors in their mutual hybridization.
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Oligodesoxirribonucleótidos
/
ADN de Cadena Simple
/
ADN Encadenado
Idioma:
En
Revista:
Chem Commun (Camb)
Asunto de la revista:
QUIMICA
Año:
2018
Tipo del documento:
Article
País de afiliación:
China