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Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity.
Schnabel, Christiane L; Wimer, Christine L; Perkins, Gillian; Babasyan, Susanna; Freer, Heather; Watts, Christina; Rollins, Alicia; Osterrieder, Nikolaus; Wagner, Bettina.
Afiliación
  • Schnabel CL; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
  • Wimer CL; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
  • Perkins G; Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
  • Babasyan S; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
  • Freer H; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
  • Watts C; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
  • Rollins A; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA.
  • Osterrieder N; Institut für Virologie, Freie Universität Berlin, Philippstrasse 13, 10115, Berlin, Germany.
  • Wagner B; Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA. bw73@cornell.edu.
BMC Vet Res ; 14(1): 245, 2018 Aug 22.
Article en En | MEDLINE | ID: mdl-30134896
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Virulencia / Herpesvirus Équido 1 / Infecciones por Herpesviridae / Factores de Virulencia / Enfermedades de los Caballos Límite: Animals Idioma: En Revista: BMC Vet Res Asunto de la revista: MEDICINA VETERINARIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Proteínas Virales / Virulencia / Herpesvirus Équido 1 / Infecciones por Herpesviridae / Factores de Virulencia / Enfermedades de los Caballos Límite: Animals Idioma: En Revista: BMC Vet Res Asunto de la revista: MEDICINA VETERINARIA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos