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3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo.
Rashidi, Hassan; Luu, Nguyet-Thin; Alwahsh, Salamah M; Ginai, Maaria; Alhaque, Sharmin; Dong, Hua; Tomaz, Rute A; Vernay, Bertrand; Vigneswara, Vasanthy; Hallett, John M; Chandrashekran, Anil; Dhawan, Anil; Vallier, Ludovic; Bradley, Mark; Callanan, Anthony; Forbes, Stuart J; Newsome, Philip N; Hay, David C.
Afiliación
  • Rashidi H; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK.
  • Luu NT; Centre for Liver Research, Institute of Immunology and Immunotherapy and National Institute for Health Research Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham, Birmingham, UK.
  • Alwahsh SM; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK.
  • Ginai M; Institute of Bioengineering, The University of Edinburgh, King's Buildings, Edinburgh, EH9 3DW, UK.
  • Alhaque S; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK.
  • Dong H; School of Chemistry, University of Edinburgh, Kings Buildings, EH9 3FJ, Edinburgh, UK.
  • Tomaz RA; Anne McLaren Laboratory, Wellcome Trust-MRC Stem Cell Institute, University of Cambridge, Cambridge, CB2 0SZ, UK.
  • Vernay B; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK.
  • Vigneswara V; Centre for Liver Research, Institute of Immunology and Immunotherapy and National Institute for Health Research Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham, Birmingham, UK.
  • Hallett JM; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK.
  • Chandrashekran A; Child Health Clinical Academic Group, MRC Centre for Transplantation, King's College London, London, UK.
  • Dhawan A; Child Health Clinical Academic Group, MRC Centre for Transplantation, King's College London, London, UK.
  • Vallier L; Anne McLaren Laboratory, Wellcome Trust-MRC Stem Cell Institute, University of Cambridge, Cambridge, CB2 0SZ, UK.
  • Bradley M; School of Chemistry, University of Edinburgh, Kings Buildings, EH9 3FJ, Edinburgh, UK.
  • Callanan A; Institute of Bioengineering, The University of Edinburgh, King's Buildings, Edinburgh, EH9 3DW, UK.
  • Forbes SJ; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, EH16 4UU, UK.
  • Newsome PN; Centre for Liver Research, Institute of Immunology and Immunotherapy and National Institute for Health Research Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham, Birmingham, UK.
  • Hay DC; Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Arch Toxicol ; 92(10): 3117-3129, 2018 10.
Article en En | MEDLINE | ID: mdl-30155720
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_cobertura_universal Asunto principal: Trasplante de Hígado / Ingeniería de Tejidos / Células Madre Pluripotentes / Hígado Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 2_ODS3 Problema de salud: 2_cobertura_universal Asunto principal: Trasplante de Hígado / Ingeniería de Tejidos / Células Madre Pluripotentes / Hígado Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido