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Targeting quiescent leukemic stem cells using second generation autophagy inhibitors.
Baquero, Pablo; Dawson, Amy; Mukhopadhyay, Arunima; Kuntz, Elodie M; Mitchell, Rebecca; Olivares, Orianne; Ianniciello, Angela; Scott, Mary T; Dunn, Karen; Nicastri, Michael C; Winkler, Jeffrey D; Michie, Alison M; Ryan, Kevin M; Halsey, Christina; Gottlieb, Eyal; Keaney, Erin P; Murphy, Leon O; Amaravadi, Ravi K; Holyoake, Tessa L; Helgason, G Vignir.
Afiliación
  • Baquero P; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
  • Dawson A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
  • Mukhopadhyay A; Paul O'Gorman Leukemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK.
  • Kuntz EM; Cancer Research UK, Beatson Institute, Garscube Estate, Glasgow, G61 1BD, UK.
  • Mitchell R; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
  • Olivares O; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
  • Ianniciello A; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
  • Scott MT; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
  • Dunn K; Paul O'Gorman Leukemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK.
  • Nicastri MC; Department of Medicine and Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Winkler JD; Department of Medicine and Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Michie AM; Paul O'Gorman Leukemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK.
  • Ryan KM; Cancer Research UK, Beatson Institute, Garscube Estate, Glasgow, G61 1BD, UK.
  • Halsey C; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK.
  • Gottlieb E; Cancer Research UK, Beatson Institute, Garscube Estate, Glasgow, G61 1BD, UK.
  • Keaney EP; Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.
  • Murphy LO; Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts, 02139, USA.
  • Amaravadi RK; Department of Medicine and Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Holyoake TL; Paul O'Gorman Leukemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G12 0ZD, UK.
  • Helgason GV; Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, G61 1QH, UK. Vignir.Helgason@Glasgow.ac.uk.
Leukemia ; 33(4): 981-994, 2019 04.
Article en En | MEDLINE | ID: mdl-30185934

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_leukemia Asunto principal: Poliaminas / Autofagia / Células Madre Neoplásicas / Leucemia Mielógena Crónica BCR-ABL Positiva / Resistencia a Antineoplásicos / Aminoquinolinas Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Contexto en salud: 6_ODS3_enfermedades_notrasmisibles Problema de salud: 6_leukemia Asunto principal: Poliaminas / Autofagia / Células Madre Neoplásicas / Leucemia Mielógena Crónica BCR-ABL Positiva / Resistencia a Antineoplásicos / Aminoquinolinas Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Reino Unido
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