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IL7R overexpression in adult acute lymphoblastic leukemia is associated to JAK/STAT pathway mutations and identifies patients who could benefit from targeted therapies.
Gianfelici, Valentina; Messina, Monica; Paoloni, Francesca; Peragine, Nadia; Lauretti, Alessia; Fedullo, Anna Lucia; Di Giacomo, Filomena; Vignetti, Marco; Vitale, Antonella; Guarini, Anna; Chiaretti, Sabina; Foà, Robin.
Afiliación
  • Gianfelici V; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Messina M; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Paoloni F; b GIMEMA Data Center, GIMEMA , Rome , Italy.
  • Peragine N; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Lauretti A; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Fedullo AL; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Di Giacomo F; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Vignetti M; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Vitale A; b GIMEMA Data Center, GIMEMA , Rome , Italy.
  • Guarini A; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Chiaretti S; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
  • Foà R; a Hematology, Department of Cellular Biotechnologies and Hematology , Sapienza University , Rome , Italy.
Leuk Lymphoma ; 60(3): 829-832, 2019 03.
Article en En | MEDLINE | ID: mdl-30188230
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Expresión Génica / Factores de Transcripción STAT / Quinasas Janus / Subunidad alfa del Receptor de Interleucina-7 / Leucemia-Linfoma Linfoblástico de Células T Precursoras Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Italia
Texto completo
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Transducción de Señal / Expresión Génica / Factores de Transcripción STAT / Quinasas Janus / Subunidad alfa del Receptor de Interleucina-7 / Leucemia-Linfoma Linfoblástico de Células T Precursoras Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Leuk Lymphoma Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2019 Tipo del documento: Article País de afiliación: Italia