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Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach.
Bassi, Zuni I; Fillmore, Martin C; Miah, Afjal H; Chapman, Trevor D; Maller, Claire; Roberts, Emma J; Davis, Lauren C; Lewis, Darcy E; Galwey, Nicholas W; Waddington, Kirsty E; Parravicini, Valentino; Macmillan-Jones, Abigail L; Gongora, Celine; Humphreys, Philip G; Churcher, Ian; Prinjha, Rab K; Tough, David F.
Afiliación
  • Bassi ZI; Protein Degradation DPU, Future Pipelines Discovery, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Fillmore MC; NCE-MD Medicinal Chemistry UK Team, R&D Platform Technology & Science, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Miah AH; Protein Degradation DPU, Future Pipelines Discovery, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Chapman TD; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Maller C; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Roberts EJ; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Davis LC; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Lewis DE; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Galwey NW; Target Sciences Statistics, R&D Target Sciences, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Macmillan-Jones AL; Protein Degradation DPU, Future Pipelines Discovery, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Gongora C; Institut de Recherche en Cancérologie de Montpellier, INSERM U1194, Université de Montpellier , Montpellier F-34298 , France.
  • Humphreys PG; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Prinjha RK; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
  • Tough DF; Epigenetics DPU, Immuno-Inflammation and Oncology Therapy Area, GlaxoSmithKline , Medicines Research Centre , Stevenage SG1 2NY , United Kingdom.
ACS Chem Biol ; 13(10): 2862-2867, 2018 10 19.
Article en En | MEDLINE | ID: mdl-30200762
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Piridazinas / Benzoatos / Factores de Transcripción p300-CBP Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: ACS Chem Biol Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
Añadir a Mi BVS
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Piperidinas / Piridazinas / Benzoatos / Factores de Transcripción p300-CBP Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: ACS Chem Biol Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido