Impact of RSV Coinfection on Human Bocavirus in Children with Acute Respiratory Infections.
J Trop Pediatr
; 65(4): 342-351, 2019 08 01.
Article
en En
| MEDLINE
| ID: mdl-30202992
ABSTRACT
OBJECTIVE:
The objective of this study was to assess epidemiological and clinical features of human bocavirus (HBoV) coinfection with other viruses.METHOD:
Children coinfected with HBoV between January 2012 and December 2014 were enrolled and retrospectively reviewed.RESULT:
A total of 984 patients were stratified into five groups HBoV infection alone (n = 249), respiratory syncytial virus (RSV) infection alone (n = 649), HBoV coinfection with RSV (n = 28), with human rhinovirus (HRV) (n = 39) and with other virus (n = 19). Length of hospitalization was longer in HBoV coinfection with RSV group than HBoV (9.0 days vs. 7.0 days, p = 0.001), RSV (9.0 days vs. 8.0 days, p = 0.016) infection alone group. Pneumonia was more common in the HBoV coinfection with RSV group compared with the HBoV, RSV infection alone group, respectively (75.0% vs. 44.2%, 31.3%, p < 0.001). HBoV DNA copy numbers (383 000 copies/ml) were positively correlated with the length of hospitalization (r = 0.334, p < 0.001).CONCLUSION:
HBoV coinfection with RSV increases HBoV infection severity.Palabras clave
Texto completo:
1
Colección:
01-internacional
Base de datos:
MEDLINE
Asunto principal:
Neumonía
/
Infecciones del Sistema Respiratorio
/
Nasofaringe
/
Infecciones por Virus Sincitial Respiratorio
/
Infecciones por Parvoviridae
/
Bocavirus Humano
/
Coinfección
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Región como asunto:
Asia
Idioma:
En
Revista:
J Trop Pediatr
Año:
2019
Tipo del documento:
Article
País de afiliación:
China