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Engineering of a tumor cell-specific, cytosol-penetrating antibody with high endosomal escape efficacy.
Kim, Ji-Sun; Park, Jae-Yeong; Shin, Seung-Min; Park, Seong-Wook; Jun, Sei-Yong; Hong, Jin-Sun; Choi, Dong-Ki; Kim, Yong-Sung.
Afiliación
  • Kim JS; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
  • Park JY; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
  • Shin SM; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
  • Park SW; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
  • Jun SY; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
  • Hong JS; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea.
  • Choi DK; ORUM Therapeutics Inc., Daejeon, 34050, Republic of Korea.
  • Kim YS; Department of Molecular Science and Technology, Ajou University, Suwon, 16499, Republic of Korea; Department of Allergy and Clinical Immunology, Ajou University Medical Center, Suwon, 16499, Republic of Korea. Electronic address: kimys@ajou.ac.kr.
Biochem Biophys Res Commun ; 503(4): 2510-2516, 2018 09 18.
Article en En | MEDLINE | ID: mdl-30208519
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Ingeniería de Proteínas / Sistemas de Liberación de Medicamentos / Citosol / Péptidos de Penetración Celular Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Inmunoglobulina G / Ingeniería de Proteínas / Sistemas de Liberación de Medicamentos / Citosol / Péptidos de Penetración Celular Límite: Humans Idioma: En Revista: Biochem Biophys Res Commun Año: 2018 Tipo del documento: Article