ACSS2 promotes systemic fat storage and utilization through selective regulation of genes involved in lipid metabolism.

Huang, Zhiguang; Zhang, Menglu; Plec, Abigail A; Estill, Sandi Jo; Cai, Ling; Repa, Joyce J; McKnight, Steven L; Tu, Benjamin P

Huang, Zhiguang; Zhang, Menglu; Plec, Abigail A; Estill, Sandi Jo; Cai, Ling; Repa, Joyce J; McKnight, Steven L; Tu, Benjamin P.

Afiliación

Huang Z; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Zhang M; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Plec AA; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Estill SJ; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Cai L; Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Repa JJ; Children's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390.
McKnight SL; Department of Physiology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Tu BP; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390; steven.mcknight@utsouthwestern.edu benjamin.tu@utsouthwestern.edu.

Proc Natl Acad Sci U S A ; 115(40): E9499-E9506, 2018 10 02.

Article en En | MEDLINE | ID: mdl-30228117

Asunto(s)

Acetato CoA Ligasa/metabolismo; Tejido Adiposo/metabolismo; Hígado Graso/metabolismo; Regulación de la Expresión Génica; Metabolismo de los Lípidos; Hígado/metabolismo; Acetato CoA Ligasa/genética; Acetilcoenzima A/genética; Acetilcoenzima A/metabolismo; Tejido Adiposo/patología; Animales; Hígado Graso/genética; Hígado Graso/patología; Hígado/patología; Ratones; Ratones Noqueados

Palabras clave

acetate; epigenetics; fatty liver disease; metabolism; obesity

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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Acetato CoA Ligasa / Tejido Adiposo / Regulación de la Expresión Génica / Metabolismo de los Lípidos / Hígado Graso / Hígado Límite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2018 Tipo del documento: Article

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