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Design, synthesis and evaluation of new classes of nonquaternary reactivators for acetylcholinesterase inhibited by organophosphates.
Wei, Zhao; Bi, Huanglei; Liu, Yan-Qin; Nie, Hui-Fang; Yao, Lin; Wang, Sheng-Zheng; Yang, Jun; Wang, Yong-An; Liu, Xueying; Zheng, Zhi-Bing.
Afiliación
  • Wei Z; Department of Medicinal Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 300071, China. Electronic address: weizhaobruce@163.com.
  • Bi H; Laboratory of Computer-Aided Drug Design & Discovery, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China; Department of Pharmacy, The 253th Hospital of PLA, Hohhot 010051, China.
  • Liu YQ; Department of Military Toxicology and Biochemical Pharmacology, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China.
  • Nie HF; Department of Medicinal Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 300071, China.
  • Yao L; Department of Medicinal Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 300071, China.
  • Wang SZ; Department of Medicinal Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 300071, China.
  • Yang J; Department of Military Toxicology and Biochemical Pharmacology, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China.
  • Wang YA; Department of Military Toxicology and Biochemical Pharmacology, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences, Beijing 100850, China.
  • Liu X; Department of Medicinal Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 300071, China.
  • Zheng ZB; Laboratory of Computer-Aided Drug Design & Discovery, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China. Electronic address: zzbcaptain@aliyun.com.
Bioorg Chem ; 81: 681-688, 2018 12.
Article en En | MEDLINE | ID: mdl-30265992
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plaguicidas / Acetilcolinesterasa / Diseño de Fármacos / Inhibidores de la Colinesterasa / Activadores de Enzimas / Agentes Nerviosos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2018 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Base de datos: MEDLINE Asunto principal: Plaguicidas / Acetilcolinesterasa / Diseño de Fármacos / Inhibidores de la Colinesterasa / Activadores de Enzimas / Agentes Nerviosos Límite: Humans Idioma: En Revista: Bioorg Chem Año: 2018 Tipo del documento: Article